GPCR Dock 2021


We will assess both the accuracy of GPCR structure prediction and the accuracy of ligand docking. The assessment criteria include (but are not limited to) the following:

  1. Accuracy of predicting TM bundle structure
  2. Accuracy of predicting ECLs
  3. Accuracy of predicting the ligand binding site
  4. Accuracy of ligand docking (ligand RMSD and interactions/contacts)

Please refer to prior publications [1-3] to get a better idea of GPCR Dock model assessment criteria. We reserve the right to revise and update these criteria in a way that individual targets dictate. Please do not hesitate to contact us (Irina Kufareva:, or Suwen Zhao: with questions and suggestions.


[1] Community-wide assessment of GPCR structure modelling and ligand docking: GPCR Dock 2008. Nat Rev Drug Discov. 8, 455-463, 2009.

[2] Status of GPCR modeling and docking as reflected by community-wide GPCR Dock 2010 assessment. Structure. 19, 1108-1126, 2011.

[3] Advances in GPCR modeling evaluated by the GPCR Dock 2013 assessment: meeting new challenges. Structure. 22, 1120-1139, 2014.